The way you've worded your question is a bit ambiguous, so forgive me if my reading-between-the-lines is reading incorrectly, but it seems like you're saying that modern Quantum Field Theory might be unsatisfying to someone like Newton, because you think QFT requires instantaneous action at a distance - ie non-locality - and you have other unspecified problems with the idea of fields.
I think the nature of your question might change if you found out that it's NOT a given, at all, that QFT involves non-local causality, and in fact many physicists believe simultaneously in QM, QFT and local-only causality.
If it's true that Newton would be unsatisfied with any non-local causality in modern theories, then you can rest easy knowing there are interpretations of QM and QFT which maintain local causality - perhaps Newton and Einstein would prefer those interpretations.